Biologics expertise to
accelerate your product to market

We partner with you from discovery to GMP manufacturing, delivering services for monoclonal antibodies, recombinant proteins, and mRNA therapeutics.

Your partner on the journey
from curiosity to cureSM

Discovery

Make the most of your molecule

Comprehensive antibody discovery and engineering services to help you identify, optimize and characterize new leads and deliver molecules demonstrating the desired functionality and reactivity.

Antibody production via transient CHO, HEK293 and other expression platforms at milligrams to gram quantities. Unparalleled analytical capability to enhance recombinant antibody quality.

Full-scale capabilities from molecular design and construction to performing expression purification and characterization across mammalian, microbial and baculovirus systems.

Platform

TunaCHO™, a proprietary technology platform for CHO transient production, delivering the highest production yield compared to other commercial cell lines

Development

Validate and accelerate your compound

Process development

Commercial mindset from the start to accelerate timelines to clinic.

  • Optimize cell productivity in single-use bioreactors (SUB)
  • Performed for all protein-based technologies
  • Demonstrated success with purification schemes for hundreds of unique proteins for pre-clinical toxicology material

CHO-GSNSM platform stable cell line development service

Our platform uses its proprietary cell line, custom stable expression vectors, and glutamine synthetase (GS) selection technology, maximizing purity and yield while minimizing the time between development and toxicology studies.

Analytical method development and services to optimize assay design, capacity and execution

Comprehensive method development meeting USP, Ph. Eur., and FDA guidelines

Expertise from discovery to cGxP therapeutic testing for all service types

Formulation development services

Fully integrated formulation development programs that emphasize critical quality attributes with ICH stability guidelines and manufacturability in mind

mRNA development services

End-to-end solutions covering mRNA synthesis, formulation and lipid nanoparticle fill-finish

Manufacturing

Rely on our expertise

Our complete suite of services and solutions for mRNA, monoclonal antibodies and recombinant proteins.

Drug substance

Our Hopkinton, MA facility is ISO 13485:2016 certified and provides biomanufacturing services for GMP and BPG production of mRNA, protein therapeutics and vaccines, and therapeutic antibodies.

  • Established quality system supports production of early-phase bulk drug and diagnostic products
  • End-to-end solutions cover mRNA, protein and antibody large scale production, in-process testing and batch release, lipid nanoparticle (LNP) fill-finish — all manufactured in ISO 7 suites with GMP-compliant single-use equipment
Drug product

Our Glasgow, UK and Camarillo, CA sites offer expertise and capabilities for sterile drug product manufacturing from early clinical through large-scale supply.

  • Providing a complete suite of services for all sterile dosage forms — liquid, suspension or lyophilized
  • Covering a broad range of therapeutics in mRNA, proteins, mAbs, peptides, oligonucleotides to deliver large-scale fill-finish needs

The power of a partnership with Curia

Biologics Formulation and Fill-Finish Capabilities at Curia

With over 30 years of experience formulating both large and small molecules for injection, we can identify the quality attributes that impact the clinical performance and safety of formulations, analyze the manufacturability of dosage forms, and assess stability in primary packaging. Watch video

Resources

Learn more

Curia is a Contract Development and Manufacturing Organization with over 30 years of experience, an integrated network of 29 global sites and over 3,500 employees partnering with customers to make treatments broadly accessible to patients. Our biologics and small molecule offering spans discovery through commercialization, with integrated regulatory and analytical capabilities. Our scientific and process experts and state-of-the-art facilities deliver best-in-class experience across drug substance and drug product manufacturing. From curiosity to cure, we deliver every step to accelerate and sustain life-changing therapeutics.