Developability Analysis
Evaluating the developability of therapeutic drug candidates early can help circumvent potential issues in late-stage development. These evaluations include the drug candidate’s biophysical and chemical properties assessment. At LakePharma, in silico predictive tools and a series of fast & small-scale assessments are employed to serve as additional selection criteria for better and safe therapeutic leads.
LakePharma offers three developability assessment packages:
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Key Highlights
In silico Analysis: Application of Bioinformatic Tools
- Heavy and light chain variable region liability analysis
- VH and VL analysis with identification of core residues with potential affinity to MHC class II
Rapid Integrity Assessments and Formulation Studies for Drug Candidates
- Polyspecificity and integrity assessment can be completed in 2-3 weeks
- Formulation studies can be completed in 5 - 6 weeks, including the standard 2 weeks of incubation for accelerated stress conditions
Robust Bioanalytical Assays and Formulation Studies with Minimal Materials Required
- The standard panel includes common formulations used for commercial antibodies
- Various bioanalytical assays and characterization tools are provided
- A small amount of materials are needed for the bioanalytical assays and formulation studies
Download our Antibody Discovery Engineering Services
Brochure by clicking here
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| Catalog # | Name | Timeline | Price |
|---|---|---|---|
| 1000 | Developability Package 1 | 1 week | $2,000 |
| 2000 | Developability Package 2 | 3 weeks | $14,300 |
| 3000 | Developability Package 3 | 6 weeks | $99,000 |
| 60000 | Bioanalytical Setup Fee (may be applied to any bioanalytical assay containing <10 samples) | $550 |