Catalog #1000

Title:
Developability Package 1

Description:

Developability Assessment – Package 1


Package includes:

1. In Silico Sequence Liability Analysis 

    - Heavy and light chain variable region liability analysis including but not limited to N-linked glycosylation, deamidation, isomerization, pyroglutamate formation, and oxidation.

 

2.  In Silico Immunogenicity Analysis

    - Variable heavy and variable light chain sequences are analyzed and nice core residues with potential affinity to the binding cleft of MHC class II molecules are identified.


Scope:

Deliverable:
  • In silico Sequence Liability Analysis
  • In silico Immunogenicity Analysis

Material Required:
  • Antibody heavy and light chain sequences

Timeline:
1 week

Price:
$2,000