Protein engineering has greatly benefited from the advent of in vitro display platforms, where individual or large libraries of peptides or proteins are displayed on the surface of mammalian, yeast, or bacterial cells or even bacteriophage capsids.
Phage vs Yeast Display
Phage display is based on the isolation of large pools of antibody genes cloned into different scaffolds such as antigen-binding fragments (Fab), single-chain variable fragments (scFv), or VHH (nanobody). Yeast display, on the other hand, involves the insertion of a large spectrum of antibody sequences into yeast surface display vectors.
LakePharma offers a variety of libraries
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Discovery of Potent, Functional Anti-BTLA, and Anti-TIGIT Monoclonal Antibodies using Hybridoma and Phage Display Platform webinar recording available NOW!