Antibody Discovery & Engineering
LakePharma offers multiple technology platforms to discover novel monoclonal antibodies:
1. Hybridoma technology: comprehensive, customized hybridoma campaigns for therapeutic antibody discovery
2. Naïve, synthetic, immune phage, or immune yeast libraries: multiple licensed phage libraries (XOMA, Twist, etc.) as well as immunization protocols with in-line library construction for therapeutic or diagnostic antibody discovery
Lakepharma provides unparalleled antibody engineering services:
1.
Stand-alone or combined (HuMAT) humanization and
affinity maturation workflows of potential antibody candidates via phage or
yeast display of light chain-shuffled or CDR-mutagenic libraries
2. Full kinetic characterization and epitope binning using state-of-the-art array SPR Carterra LSA and Octet BLI platforms