The gene-engineered Chinese Hamster Ovary (CHO) cell line, adapted to manufacturing conditions by LakePharma, is offered by LakePharma as a parental cell line in its stable cell line generation platform and available for license and commercial use by clients.
CHO-GSN™ is our proprietary CHO stable cell line development platform. LakePharma adapted Horizon’s CHO cell to suspension growth in commercially available animal component-free, chemically defined media, and carried out a full evaluation of protein expression. The decision to partner was based upon successful evaluation, showing significantly higher antibody titers at the stable pool stage relative to LakePharma’s previous system.
- Robust final cell line performance
- High titer with stronger GS selection
- Generational stability >80 generations demonstrated
- Upstream and downstream process development
- Royal-free platform
Download our CHO-GSN™ presentation by clicking here.