TunaCHO™ is a proprietary technology platform for CHO transient protein production. It uses suspension-adapted CHO cells (CHO-K1 parental cell line) and the process is animal-product free. It was developed by LakePharma and partners.
CHO cells originated from the same cell line used in CHO-GSN™. Together these two CHO platforms offer transient and stable production.
TunaCHO™ can be applied at various scales, ranging from 10 mL shake tubes to 10 L WAVEs. It has shown production titers greater than 2 grams per liter in shake flasks. Importantly, production titers are consistent at different scales.
Since its launch in 2017, TunaCHO™ has been used to produce over 20,000 transient productions and has become a favorite mammalian production system.
Transient recombinant antibody production in the TunaCHO™ platform. The average yield is 4.2 mg/10mL culture.
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