- Molecular Biology
- Viral Vectors & Cell Engineering
- Protein Engineering & Production
- Antibody Discovery & Engineering
- Antibody Production
-
Analytics & Formulation
- Overview
- Purity Analysis by CE-SDS
- Aggregation Analysis
- Charge Variant Analysis
- De Novo Antibody Sequencing
- Intact Mass Analysis
- Sequence Confirmation by Mass Spectrometry
- N-terminal Sequencing
- Post-Translational Modification
- N-glycan Analysis
- Thermostability Analysis
- Stability Analysis
- Formulation Development
- Developability Analysis
- FAQs
- R&D and cGxP Bioassay Development
- Protein Chemistry
- Development & Manufacturing in LakePharma Hayward, CA
- Development & Manufacturing in LakePharma Hopkinton, MA
- Consulting Services
Process Development
LakePharma has a wide range of bioreactor and purification equipment enabling technology transfers to scale-down models on either multi-use or single-use platforms. Our PD team can help fill process gaps via de novo development, filtration and chromatography optimization, or help mitigate risk with adaptation to single-use technology.
cGMP process design & development:
- Proof of concept
- Process miniaturization and optimization
- Depth filter, UF/DF, and chromatography process optimization
- Seamless tech transfer featuring single use technology
- Reliable scale-up process utilizing single-use stirred tank reactors (STRs) and chromatography systems
- Comprehensive process monitoring and control
