- Molecular Biology
- Viral Vectors & Cell Engineering
- Protein Engineering & Production
- Antibody Discovery & Engineering
- Antibody Production
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Analytics & Formulation
- Overview
- Purity Analysis by CE-SDS
- Aggregation Analysis
- Charge Variant Analysis
- De Novo Antibody Sequencing
- Intact Mass Analysis
- Sequence Confirmation by Mass Spectrometry
- N-terminal Sequencing
- Post-Translational Modification
- N-glycan Analysis
- Thermostability Analysis
- Stability Analysis
- Formulation Development
- Developability Analysis
- FAQs
- R&D and cGxP Bioassay Development
- Protein Chemistry
- Development & Manufacturing in LakePharma Hayward, CA
- Development & Manufacturing in LakePharma Hopkinton, MA
- Consulting Services
AAV
The Vector Technology group utilizes the mammalian and baculovirus platforms for the production of AAV, with a focus on vector engineering and optimization, process development, and scale-up production. The technical team at LakePharma has over 16 years of experience utilizing suspension insect cell lines and the baculovirus system for the production of recombinant proteins and the AAV platform expands on those capabilities. Extensive characterization capabilities are also available with LakePharma's assay group.
Key Features of AAV Production Platform
Mammalian - HEK293 production platform - Suspension and adherent options - Helper-free system - Up to 100L culture production | Baculovirus - Suspension-based culture (Sf9) - High titer baculovirus production within 2 weeks - BIIC research cell banks - Up to 100L culture production |
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Click here to download our Viral Vector Presentation
Case study: Purity and Identity Characterization of AAV Capsid Particles by LC-MS Methods in collaboration with Agilent